Mitochondria comprise 15–20% of the proteins of a cell. Only very few mitochondrial proteins are synthesized inside the organelle. Over 98% of mitochondrial proteins are made as preproteins in the ...
Proteomic studies revealed that mitochondria contain ∼1,000 (in yeast) to 1,500 (in humans) different proteins and led to the recent identification of new mitochondrial import pathways and components.