A new study found that a single mutation to the hemagglutinin protein of an H5N1 virus isolated from a dairy worker in Texas this spring switched the protein’s binding specificity from avian- to human ...

A protein that is a key modulator of fat, glucose and cholesterol levels in the body usually works in tandem with another ...

BUFFALO, N.Y. – Touch a hot plate and your hand flies back. While the response is almost instant, researchers are still working to better understand the molecular mechanisms behind these sensations of ...

The SARS-CoV-2 virus is continuously evolving and structural changes to the virus may impact the efficacy of antibody therapies and vaccines. A study describes the structural and functional landscape ...

Protein glycosylation is a post-translational/co-translational covalent attachment of glycans to the amino acid side chains of proteins. Severe acute respiratory ...

Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

Lefkowitz started to trace cell receptors in 1968. Using radioactivity, he managed to unveil several receptors, including one for adrenalin, the β-adrenergic receptor. His team then extracted the ...

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability. The cause, which has been well-studied, is the loss of fragile X mental retardation protein (FMRP)—a genetic ...

Researchers created a tool capable of comprehensively mapping crucial interactions underlying drug efficacy in one superfamily of cell receptors. One in every three FDA-approved drugs targets a single ...

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.