In summary, macrophages secrete IFN-β, activating the IFN-β-IFNAR-p-STAT1 axis in MICFs, leading to increased secretion of CCL2/7/12 chemokines and subsequent recruitment of more IFN-β-secreting ...

Researchers from ITMO, Skoltech, and MIPT have developed a new method of photothermal cancer immunotherapy that allows for highly accurate control of the immune response inside the tumor itself. The ...

The research uncovers a previously unappreciated mechanism by which macrophages influence the fate of CFs post-MI. It demonstrates that macrophage-derived IFN-β stimulates the IFN-β-IFNAR-p-STAT1 axis ...

Engineered bacteria reprogram tumor macrophages and direct copper into cancer cells, triggering cell death and systemic immunity without damaging healthy tissue. (Nanowerk Spotlight) Tumors do not ...

Gram-stained section of a macrophage with ingested S epidermidis bacteria, seen as purple granules within its cytoplasm. In this stain, the nucleus appears pale, with a reddish nucleolus. It is ...

Ness-Ziona, Israel, Dec. 11, 2024 (GLOBE NEWSWIRE) -- Enlivex Therapeutics Ltd. (Nasdaq: ENLV, the “Company”), a clinical-stage macrophage reprogramming immunotherapy company, today announced that the ...

Metastasis, or cancer spreading, is complex and still largely mysterious. As a tumor grows, it interacts constantly with the surrounding environment, including blood vessels, signaling molecules, and ...

Tsukuba, Japan—Acid resistance is a crucial property that enterobacteria must possess to withstand host acidic environments during infection, including the gastrointestinal tract and macrophage ...